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Nuclear Receptors and Genetic Disease

By: Thomas P. Burris Edward R.B. McCabe (Author)

Ksh 28,800.00
Format :

Format(s): DRM PDF DRM EPUB

ISBN-13: 9780080917146

Publisher: Elsevier Science

Imprint: Academic Press

Publication Date: September 6th, 2000

Country of Publication: GB

Language: English

Pages: 419

Physical Edition EAN: 9780121461607

Category: Medical genetics , Nuclear chemistry, photochemistry & radiation , Molecular biology

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  • Description

  • Author Bio

Nuclear Receptors and Genetic Disease provides the first compilation of the role of nuclear hormones in health and disease and incorporates the latest breakthroughs in the field. It provides comprehensive reviews of the major receptors prepared by the acknowledged experts in each area. Each chapter provides information on the history, physiology, structure, mechanism of action, genetics, pathophysiology, disease diagnosis, and disease treatment for a particular nuclear receptor. Each chapter also includes a table showing all the known mutations of the respective nuclear receptor with the corresponding clinical disorder.Receptors included in this book are: The Nuclear Receptor Superfamily Thyroid Hormone Receptors Estrogen and Progesterone Receptors The Androgen Receptor DAX-1 and Related Orphan Receptors The Vitamin D Receptor Retinoid Receptors Mineralocorticoid and Glucocorticoid Receptors Hepatocyte Nuclear Factor 4 a Peroxisome Proliferator Activated Receptors Coactivators and Corepressors

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