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Review of DOD's Approach to Deriving an Occupational Exposure Level for Trichloroethylene

By: and Medicine Engineering National Academies of Sciences Division on Earth and Life Studies Board on Environmental Studies and Toxicology Committee to Review DOD's Approach to Deriving an Occupational Exposure Limit for TCE (Author)

Ksh 8,860.00
Format :

Format(s): DRM EPUB

ISBN-13: 9780309499279

Publisher: National Academies Press

Imprint: National Academies Press

Publication Date: December 13th, 2019

Country of Publication: US

Language: English

Pages: 76

Physical Edition EAN: 9780309499248

Category: Environmental policy & protocols , Conservation of the environment , Pollution & threats to the environment

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  • Description

  • Author Bio

Trichloroethylene (TCE) is a solvent that is used as a degreasing agent, a chemical intermediate in refrigerant manufacture, and a component of spot removers and adhesives. It is produced in mass quantities but creates dangerous vapors and is an environmental contaminant at many industrial and government facilities, including facilities run by the U.S. Department of Defense (DoD). It is important to determine the safe occupational exposure level (OEL) for the solvent in order to protect the health of workers who are exposed to its vapors. However, there are concerns that the current occupational standards insufficiently protect workers from these health threats.Review of DODs Approach to Deriving an Occupational Exposure Level for Trichloroethylene makes recommendations to improve the DoDs approach to developing an OEL for TCE, strengthen transparency of the process, and improve confidence in the final OEL value. This report reviews the DoDs approach using a literature review, evidence synthesis based on weight of evidence [WOE], point-of-departure derivation, physiologically based pharmacokinetic modeling, extrapolation tools, and explores other elements of the process of deriving an OEL for TCE. It examines scientific approaches to developing exposure values and cancer risk levels, defining the scope of the problem, and improving hazard identification.

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